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Choukri Ben Mamoun, Ph.D.

Mamoun Lab

     
 
SELECTED PUBLICATIONS

Jennifer M. Reynolds, Sachiko Takebe, Jae-Yeon Choi, Kamal El Bissati, William H. Witola, April M. Bobenchik, Jeffrey C. Hoch, Dennis R. Voelker, and Choukri Ben Mamoun. Biochemical and Genetic Analysis of the Phosphoethanolamine Methyltransferase of the Human Malaria Parasite Plasmodium falciparum. (2008) J. Biol. Chem. In press

Jennifer M. Reynolds, Kamal El Bissati, Jens Brandenburg, Arthur Günzl and Choukri Ben Mamoun. Antimalarial activity of the anticancer and proteasome inhibitor bortezomib and its analog ZL3B. (2007) BMC Pharmacology, in press

William H. Witola and Choukri Ben Mamoun. Choline Induces Transcriptional Repression and Proteasomal Degradation of the Malarial Phosphoethanolamine Methyltransferase. (2007) Eukaryotic Cell, 6:1618-1624.

Sachiko Takebe, William H. Witola, Bernd Schimanski, Arthur Günzl and Choukri Ben Mamoun. Purification of Components of the Translation Elongation Factor Complex of Plasmodium falciparum by Tandem Affinity Purification. (2007) Eukaryotic Cell, 6: 584-591

Kamal ElBissati, Rachel Zufferey, William H. Witola, Nicola S. Carter, Buddy Ullman, and Choukri Ben Mamoun. The Plasma Membrane Permease PfNT1 is Essential for Purine Salvage in the Human Malaria Parasite Plasmodium falciparum. (2006) PNAS, 103: 9286-9291.

William H. Witola, Gabriella Pessi, Kamal ElBissati, Jennifer M. Reynolds and Choukri Ben Mamoun. Localization of the phosphoethanolamine methyltransferase of the human malaria parasite Plasmodium falciparum to the golgi apparatus. (2006) J. Biol. Chem. 281: 21305 - 21311.

Seong-Kyoun Kim, Kamal El Bissati, Rachel Zufferey and Choukri Ben Mamoun. Amino acids mediate colony and cell differentiation in the fungal pathogen Candida parapsilosis. (2006) Microbiology, 152: 2885-2894.

Rachel Zufferey and Choukri Ben Mamoun. Leishmania major Expresses a Single Dihydroxyacetonephosphate AcyltransferaseAcyltransferase Localized in the Glycosome, Important for Rapid Growth and Survival at High Cell Density and Essential for Virulence. (2006) J. Biol. Chem. 281: 7952 - 7959.

Gabriella Pessi and Choukri Ben Mamoun. Pathways for Phosphatidylcholine Biosynthesis: Targets and Strategies for Anti-Malarial Drugs. (2006) Future Medicine, Future Lipidology, 1: 173-180.

Gabriella Pessi, Jae-Yeon Choi, Jennifer M. Reynolds, Dennis R. Voelker and Choukri Ben Mamoun. In vivo Evidence for the Specificity of Plasmodium falciparum Phosphoethanolamine Methyltransferase and its Coupling to the Kennedy Pathway. (2005) J. Biol. Chem. 280:12461-12466.

Rachel Zufferey and Choukri Ben Mamoun. The Initial Step of Glycerolipid Metabolism in Leishmania major Promastigotes Involves a Single Glycerol-3-Phosphate Acyltransferase Enzyme Important for the Synthesis of Triacylglycerol but not Essential for Virulence. (2005) Molecular Microbiology. 56, 800 - 810.

Henri J. VIAL and Choukri BEN MAMOUN. Plasmodium lipids: Metabolism and Function. Molecular Approaches to Malaria, Edited by I. W. Sherman (ed.). I. W. Sherman (ed.). 2005 ASM Press, Washington, D. C. Chapter 17: 327 – 352.

Gabriella PESSI, Guillermo KOCIUBINSKI and Choukri BEN MAMOUN. A Pathway for Phosphatidylcholine Biosynthesis in Plasmodium falciparum Involving Phosphoethanolamine Methylation. PNAS. (2004) 101, 6206 – 6211.

Rodolphe Roggero, Rachel Zufferey, Mihaela MINCA, Eric Richier, Michele Calas, Henri Vial and Choukri Ben Mamoun. Unraveling the Mode of Action of the Anti-Malarial Choline Analog G25 in Plasmodium and Yeast. Antimicrob. Agents Chemother. (2004) 48, 2816 – 2824.

Teresa C. SANTIAGO, Rachel ZUFFEREY, Rajendra S. MEHRA, Rosalind, A. COLEMAN and Choukri BEN MAMOUN. The Plasmodium falciparum PfGatp is an Endoplasmic Reticulum Membrane Protein Important for the Initial Step of Malarial Glycerolipid Synthesis. J. Biol. Chem. (2004) 279, 9222-9232.


 

 

 
LAB MEMBERS
Choukri Ben Mamoun Principal Investigator choukri@up.uchc.edu
Kamal ElBissati Postdoctoral Fellow  
William H. Witola Postdoctoral Fellow  
Megan Downie Postdoctoral Fellow  
Seong-Kyoun Kim Postdoctoral Fellow  
Arunima Mishra Postdoctoral Fellow  
April Bobenchik Student  
Dianna Schwarz Research Assistant  
 
ROTATIONS