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Barbara E. Kream, Ph.D.

Kream Lab

 
PUBLICATIONS

Sher LB, Woitge HW, Adams DJ, Krozowski Z, Harrison JR and Kream BE (2003) Transgenic expression of 11ß-hydroxysteroid dehydrogenase type 2 in osteoblasts reveals an anabolic role for endogenous glucocorticoids in bone. Submitted.

Nervina JM, Tetradis S, Huang, Y, Harrison D, Molina C and Kream BE (2003) Expression of inducible cAMP early repressor is coupled to the cAMP-protein kinase A signaling pathway in osteoblasts. Bone 32:483-490.

Raisz LG, Kream BE and Lorenzo JA (2002) Metabolic Bone Disease, in Williams Textbook of Endocrinology, 10th ed, JD Wilson, DW Foster, HM Kronenberg, PR Larsen (eds). WB Saunders Company, Philadelphia, PA, chapter 27, pp 1373-1410.

Harrison JR, Woitge HW and Kream BE (2002) Genetic approaches to determine the role of glucocorticoid signaling in osteoblasts. Endocrine 17:37-42.

Kream BE and Lukert BP (2001) Clinical and basic aspects of glucocorticoid action in bone. In Principles of Bone Biology, 2nd edition, vol 1, Bilezikian J, Raisz LG and Rodan GA (eds). Academic Press Inc, San Diego, CA, chapter 41, pp 723-740.

Woitge HW, Harrison JR, Ivkosic A, Krozowski Z and Kream BE (2001) Cloning and in vitro characterization of Col1a1-11ß-hydroxysteroid dehydrogenase type 2 transgenes as models for osteoblast-selective inactivation of natural glucocorticoids. Endocrinology 142:1341-1348.

Woitge H and Kream BE (2000) Calvariae from fetal mice with a disrupted Igf1 gene have reduced rates of collagen synthesis but maintain responsiveness to glucocorticoids. J Bone Miner Res 15:1956-1964.

Bogdanovic Z, Huang Y-F, Dodig M, Clark SH, Lichtler AC and Kream BE (2000) Parathyroid hormone inhibits collagen synthesis and the activity of rat Col1a1 transgenes mainly by a cAMP-mediated pathway in mouse calvariae. J Cell Biochem 77:149-158.

Huang Y-F, Harrison JR, Lorenzo JA and Kream BE (1998) Parathyroid hormone induces interleukin-6 heterogeneous nuclear and messenger RNA expression in murine calvarial organ cultures. Bone 23:327-332.

Tetradis S, Nervina JM, Nemoto K and Kream BE (1998) Parathyroid hormone induces expression of the inducible cAMP early repressor in osteoblastic MC3T3-E1 cells and mouse calvariae. J Bone Miner Res 13:1846-1851.

Kream BE , Tetradis S, LaFrancis D, Fall PM, Feyen J and Raisz LG (1997) Modulation of the effects of glucocorticoids on collagen synthesis in 21-day fetal rat calvariae by insulin-like growth factor binding protein-2. J Bone Miner Res 12:889-895.

Advani S, LaFrancis D, Bogdanovic E, Taxel P, Raisz LG and Kream BE (1997) Dexamethasone suppresses in vivo rates of bone collagen synthesis in neonatal mice. Bone 20:41-46

 
LAB MEMBERS
Barbara Kream Principal Investigator kream@nso1.uchc.edu
Denise Harrison Research Assistant dharrison@nso1.uchc.edu
Nicole Durant Laboratory Assistant durant@neuron.uchc.edu
Rebecca Cochrane Postdoctoral Fellow cochrane@student.uchc.edu
Taranpreet Chandhoke Graduate Student chandhoke@student.uchc.edu
Fei Liu Graduate Student liu@student.uchc.edu
Lorin Sher Graduate Student sher@student.uchc.edu

 

 
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