Sanchez, T, Thangada, S, Wu, MT, Kontos, CD, Wu, D, Wu, H, and Hla, T (2005) PTEN as an effector in the signaling of anti-migratory G protein-coupled receptor. Proc. Natl. Acad. Sci., USA 102:4312-4317.

Chae, SS, Paik, JH, Furneaux, H and Hla, T (2004) Requirement for sphingosine 1-phosphate receptor-1 in tumor angiogenesis demonstrated by in vivo RNA interference. J. Clin. Invest. 114:1082-1089.

Ji-Hye Paik, Athanasia Skoura, Sung-Suk Chae, Ann E. Cowan, David K. Han, Richard L. Proia and Timothy Hla (2004) Sphingosine 1-phosphate receptor regulation of N-cadherin mediates vascular stabilization. Genes and Development 18: 2392-2403.

Chae, S., Paik, J., Allende, M.L., Proia, R.L. and Hla, T. (2004) Regulation of limb development by the sphingosine 1-phosphate receptor S1p1/EDG-1 occurs via the hypoxia/ VEGF axis. Developmental Biology 268: 441-447

Sung-Hee Chang, Catherine H. Liu, Rebecca Conway, David K. Han, Kasem Nithipatikom, Ovidiu C. Trifan, Timothy F. Lane and Timothy Hla (2004) Role of Prostaglandin E2-Dependent Angiogenic Switch in COX-2-induced Breast Cancer Progression. Proc. Natl. Acad. Sci., USA 101(2):591-6.

Sanchez T, Estrada-Hernandez T, Paik JH, Wu MT, Venkataraman K, Brinkmann V, Claffey K, Hla T. (2003) Phosphorylation and action of the immunomodulator FTY720 inhibits VEGF-induced vascular permeability. J Biol Chem. 278, 47281-47290.

Sengupta S, Jang BC, Wu MT, Paik JH, Furneaux H, Hla T. (2003) The RNA-binding protein HuR regulates the expression of cyclooxygenase-2. J Biol Chem. 278:25227-33. Epub 2003 Apr 18.

Jang BC, Munoz-Najar U, Paik JH, Claffey K, Yoshida M, Hla T. (2003) Leptomycin B, an inhibitor of the nuclear export receptor CRM1, inhibits COX-2 expression. J Biol Chem. 278:2773-6. Epub 2002 Dec 04.

Bishop-Bailey D, Hla T, Warner TD. (2002) Intimal smooth muscle cells as a target for peroxisome proliferator-activated receptor-gamma ligand therapy. Circ Res. 91:210-7.

Chun J, Goetzl EJ, Hla T, Igarashi Y, Lynch KR, Moolenaar W, Pyne S, Tigyi G. (2002) International Union of Pharmacology. XXXIV. Lysophospholipid receptor nomenclature. Pharmacol Rev. 54:265-9.

Ancellin N, Colmont C, Su J, Li Q, Mittereder N, Chae SS, Stefansson S, Liau G, Hla T. (2002) Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation. J Biol Chem. 277:6667-75. Epub 2001 Dec 10.

Hla, T., Lee, M.-J., Ancellin, N., Paik, J. H., Kluk, M.J. (2001) Lysophospholipids -- receptor revelations. Science 294, 1875-1878.

Lee, M-J., Thangada, S., Paik, JH, Sapkota, GP, Ruiz, MM, Ancellin, N, Wu, M-T, Sessa, WC, Alessi, D, and Hla, T. (2001) Akt mediated phosphorylation of the G-protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis. Mol. Cell. 8, 693-704.

Liu, C. H., Chang, Sung-Hee, Trifan, O. C., Narko, K., Smith, E., Haudenschild, C., Lane, T. F. and Hla, T. (2001) Over-expression of cyclooxygenase (Cox)-2 gene is sufficient to induce tumorigenesis in transgenic mice. J. Biol. Chem. 276, 18563-18569.

Paik, Ji H, Chae, Sungsuk, Lee, Menq-Jer, Thangada, Shobha and Hla, T. (2001) Sphingosine 1-phosphate-induced endothelial cell migration requires the expression of EDG-1 and EDG-3 receptors and Rho-dependent activation of alpha vbeta3- and beta1-containing integrins. J. Biol. Chem. 276, 11830-11837.

Jang, B-C, Sanchez, T, Schaefers, HJ, Trifan, OC, Creminon, C., Liu, CH, Huang, C-K, and Hla, T. (2000) Serum withdrawal-induced post-transcriptional stabilization of cyclooxygenase (COX)-2 mRNA in MDA-MB-231 mammary carcinoma cells requires the activity of the p38 stress-activated protein (SAP) kinase. J. Biol. Chem. 275, 39507-39515.

Lee, M., Thangada, S., Claffey, K.P., Ancellin, N., Liu, C.H., Kluk, M., Volpi.. M., Sha'afi, R.I. and Hla, T. (1999) Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate. Cell 99, 301-312.

Lee, MJ, Van Brocklyn, JR, Thangada, S, Liu, CH, Hand, AR , Menzeleev, R, Spiegel, S and Hla, T. (1998) Sphingosine-1-phosphate as a ligand for the G-protein-coupled receptor EDG-1. Science 279, 1552-1555.