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Arthur Günzl

Günzl Lab

 
 
PUBLICATIONS

Nguyen, TN, B Schimanski and A Günzl (2007). Active RNA polymerase I of Trypanosoma brucei harbors a novel subunit essential for transcription. Mol Cell Biol  27, 6254-6263

Lee, JH, TN Nguyen, B Schimanski and A Günzl (2007). SL RNA gene transcription in Trypanosoma brucei requires transcription factor TFIIH. Eukaryot. Cell 6, 6, 641-649

Takebe, S, WH Witola, B Schimanski, A Günzl and C Ben Mamoun (2007). Purification of components of the translation elongation factor complex of Plasmodium falciparum by tandem affinity purification. Eukaryot. Cell  6, 584-591

Günzl, A, L Vanhamme and PJ Myler (2007). Transcription in trypanosomes: a different means to the end. In Trypanosomes – After the Genome. Eds. D Barry, J Mottram, R McCulloch and A Acosta-Serrano. Horizon Press, Pittsburgh, USA, chapter 6, pages 177-208

Skovorodkin, I, A Pimenov, I Raykhel, B Schimanski, D Ammermann and A Günzl (2007). Analysis of a-tubulin minichromosome promoters in the stichotrichous ciliate Stylonychia lemnae. Eukaryot. Cell  6, 28-36

Nguyen, TN, B Schimanski, A Zahn, B Klumpp and A Günzl (2006). Purification of an eight subunit RNA polymerase I complex in Trypanosoma brucei. Mol. Biochem. Parasitol.  149, 27-37

Schimanski, B, J Brandenburg, TN Nguyen, MJ Caimano and A Günzl (2006). A TFIIB-like protein is indispensable for spliced leader RNA gene transcription in Trypanosoma brucei. Nucleic Acids Res.  34, 1676-1684

Schimanski, B, TN Nguyen and A.
Günzl (2005). Highly efficient tandem affinity purification of trypanosome protein complexes based on a novel epitope combination. Eukaryot. Cell 4, 1942-1950

Schimanski, B, TN Nguyen and A Günzl (2005). Characterization of a multi-subunit transcription factor complex essential for SL RNA gene transcription in Trypanosoma brucei. Mol. Cell. Biol.  25, 7303-7313

Palfi, Z, B Schimanski, A Günzl, S Lücke and A Bindereif (2005). U1 small nuclear RNP from Trypanosoma brucei: a minimal U1 snRNA with unusual protein components. Nucleic Acids Res.  33, 2493-2503

Schimanski, B, G Laufer, L Gontcharova, and A Günzl (2004). The Trypanosoma brucei spliced leader RNA and rRNA gene promoters have interchangeable TbSNAP50-binding elements. Nucleic Acids Res.  32, 700-709

Günzl, A, T Bruderer, G Laufer, B Schimanski, L-C Tu, H-M Chung, and MG-S Lee (2003). RNA polymerase I transcribes procyclin genes and variant surface glycoprotein gene expression sites in Trypanosoma brucei. Eukaryot. Cell  2, 542-551

Schimanski, B, B Klumpp, G Laufer, RJ Marhöfer, P Selzer, and A Günzl . 2003. The second largest subunit of Trypanosoma brucei's multifunctional RNA polymerase I has a unique N-terminal extension domain. Mol. Biochem. Parasitol. 126: 193-200.

Günzl, A . 2003. Transcription. In Molecular Medical Parasitology. Eds J. Marr, T. Nilsen, and R. Komuniecki. Academic Press, London, UK, pp. 47-65.

Ginger, M. L., P. A. Blundell, A. M. Lewis, A. Browitt, A. Günzl , and J. D. Barry. 2002. Ex vivo and in vitro identification of a consensus promoter for VSG genes expressed by metacyclic stage trypanosomes in the tsetse. Eukaryotic Cell, 1: 1000-1009.

Günzl, A , Z Palfi, and A Bindereif. 2002. Analysis of RNA-protein complexes by oligonucleotide-targeted RNase H digestion. Methods 26: 162-169.

Laufer, G and A Günzl . 2001. In vitro competition analysis of procyclin gene and variant surface glycoprotein gene expression site transcription in Trypanosoma brucei. Mol. Biochem. Parasitol. 113: 55-65.

Skovorodkin, I, IB Zassoukhina, S Hojak, D Ammermann, and A Günzl . 2001. Minichromosomal DNA replication in the macronucleus of the hypotrichous ciliate Stylonychia lemnae is independent of chromosome-internal sequences. Chromosoma 110: 352-359.

Günzl, A , A Bindereif, E Ullu, and C Tschudi. 2000. Determinants for cap trimethylation of the U2 small nuclear RNA are not conserved between Trypanosoma brucei and higher eukaryotic organisms. Nucleic Acids Res. 28: 3702-3709.

Günzl, A and A Bindereif. 1999. Oligonucleotide-targeted RNase H protection analysis of RNA-protein complexes. Methods Mol. Biol. 118: 93-103.

Laufer, G, G Schaaf, S Bollgönn, and A Günzl . 1999. In vitro analysis of alpha-amanitin-resistant transcription in vitro from the rRNA, procyclic acidic repetitive protein and variant surface glycoprotein gene promoters in Trypanosoma brucei. Mol. Cell. Biol. 19: 5466-5473.

Skovorodkin, I, S Bollgönn, D Ammermann, and A. Günzl . 1999. Stable transfection of the hyprotrichous ciliate Stylonychia lemnae with tagged a1 tubulin minichromosomes. Eur. J. Protist. 35: 70-80.

Günzl, A , E Ullu, M Dörner, SP Fragoso, KF Hoffmann, JD Milner, Y Morita, EK Nguu, S Vanacova, S Wünsch, AO Dare, H Kwon, and C Tschudi. 1997. Transcription of the Trypanosoma brucei spliced leader RNA gene is dependent only on the presence of upstream regulatory elements. Mol. Biochem. Parasitol. 85: 67-76.

 

 
LAB MEMBERS

Arthur Günzl, Principal Investigator

 
ROTATIONS

Coming soon.